1.”Secret Wars” (1984-1985)

Regarded by many as the quintessential Marvel crossover event, “Secret Wars” brought together the universe’s mightiest heroes and villains. Spider-Man played a significant role, and it was here that he famously obtained the black symbiote suit that would eventually become Venom.

2.”The Night Gwen Stacy Died” (1973)

While not a crossover event in the traditional sense, this storyline had significant crossover implications for the Marvel Universe, as it not only affected Spider-Man but also set a precedent for character deaths in comics. The event featured the Green Goblin and has crossover elements with other heroes contemplating the morality of heroism.

3.”Maximum Carnage” (1993)

Spanning across various Spider-Man titles, “Maximum Carnage” featured a host of Marvel characters coming together to face the threat of Carnage, who had assembled his own team of villains. This street-level crossover was notable for its dark tone and has remained a fan favorite.

4.”Spider-Verse” (2014-2015)

“Spider-Verse” gathered every Spider-Person from across all dimensions to take on the Inheritors, who were preying on them. This massive crossover introduced fans to versions of Spider-Man they had never seen before and solidified its place as one of Spider-Man’s grandest events.

5.”Civil War: The Amazing Spider-Man” (2006)

As part of Marvel’s larger “Civil War,” this storyline showed the personal and political turmoil Peter Parker faced during the Superhero Registration Act debate. His decision to reveal his identity to the public was monumental and had lasting effects on his life.

6.”Infinity War” (1992)

During “Infinity War,” heroes across the universe joined forces to combat the threat of Magus and his doubles of Earth’s heroes known as doppelgangers. Although more of an ensemble piece, Spider-Man’s involvement was notable, particularly with his battles against his evil double.

7.”Spider-Island” (2011)

The entire populace of Manhattan gained spider powers in this unique storyline, forcing Spider-Man to be both a hero and a guide to these new ‘spider-citizens.’ It combined a city-wide epidemic with action-packed storytelling involving nearly all aspects of Spidey’s life.

8.”Kraven’s Last Hunt” (1987)

This crossover among various Spider-Man titles is considered one of the best for its deep psychological exploration when Kraven defeats and seemingly kills Spider-Man, only to take over his mantle in an attempt to prove himself superior.

9.”Ultimate Six” (2003-2004)

Taking place in the Ultimate Marvel universe, this series brought together five major villains from Spider-Man’s rogues’ gallery – with Norman Osborn leading them against their foe – ultimately having them clash with both Spidey and The Ultimates (this universe’s Avengers).

10.”New Avengers: Breakout ” (2005)

Although not directly a Spider-Man event, “Breakout” solidified his status as an Avenger when he joined forces with other heroes in a high-stakes breakout at The Raft super-prison, battling a plethora of his longtime enemies in a showcasing team-up dynamic.

Each event stands out for its impact on not just Spider-Man but also on the broader Marvel Universe, blending heroic struggles with personal drama that have defined what it means to be both spider and man.